Abstract. Research conducted in recent years provides more and more evidence that diet can have a significant impact on male fertility. The aim of the study was to analyze the relationship between diet, energy balance and fertility in men. A comprehensive literature search of published studies in various languages, was carried out in electronic databases. The direct analysis included 96 works published between 2008 and 2018, including 12 randomized controlled trials and 23 systematic reviews and meta-analyses. A strong adherence to a healthy dietary pattern is positively correlated with total sperm count, progressive motility and total motile escort in Akron sperm count (all p < 0.05). However, attention is drawn to the fact that foods that are considered “healthy” can sometimes contain a significant amount of pollution, which negatively affect the semen parameters. An adequate intake of antioxidants or their supplementation have been quite effective in the prevention and treatment of male infertility. The improvement of pregnancy rate after antioxidant therapy ranged in various studies from 11% to 41%. An important problem, however, may be choosing the right dose of the supplement or finding an appropriate combination of antioxidants that may be more effective than any single antioxidant. The normalization of men's body weight is beneficial for the quality of sperm and the concentration of male reproductive hormones. Further, long-term studies require the assessment of the impact of drastic weight loss after bariatric surgery on male fertility.
The brand new incidence away from infertility certainly lovers from reproductive age ranges, according to some supplies, regarding 8% so you’re able to twenty five% [1–3]. Men infertility ‘s the only reason behind infertility during the 20–30% off circumstances and one thing adding to sterility for the 50% of the many infertility cases . The newest research off male fertility usually has scientific test and you can review on the resource opinions of one’s following the semen details: frequency, overall sperm fertility, concentration, motility and you can morphology (Table step one) . Low sperm count and you will/otherwise top quality is obtainable inside ninety% regarding couples with virility difficulties . Regarding analysis out-of fertility, the fresh concentrations of male reproductive hormones also are assessed. More recently, brand new unit structure of jizz muscle, analyzed by the comparing the level of DNA fragmentation otherwise oxidative worry has been all the more taken into account. Several degree use the DNA fragmentation directory (DFI) as an indication of pregnancy achievements. Based on Evenson and you will Wixon, DFI ranges regarding 3 to 5% in healthy males, while you are a DFI away from ? 30% was with the quicker fertility . Already discussed hereditary situations, in addition to one another chromosomal aberrations and you can monogenic transform, be the cause of only about ten–15% out-of cases of male infertility . The cause having virility troubles can certainly be environmental factors. The purpose of the study were to learn the partnership between diet plan, energy harmony and you may fertility rates within the men.
Approach regarding literary works research
A comprehensive literature search of published studies in various languages, was carried out in electronic databases, including: PubMed, Cochrane Central Register of Controlled Trials (CENTRAL), Cochrane Database of Systematic Review and Google Scholar. Randomized controlled trials, observational and qualitative studies published between 2008 and 2018 (up to and including March) were included. The following keywords related to male infertility, diet, nutrients and their combinations (made by applying operators AND and OR) were used in the search: ‘male infertility’, ‘sperm quality’, ‘idiopathic oligozoospermia’, ‘astenoazospermia’, ‘oligoastenoteratozoospermia’, ‘sperm DNA damage’, ‘nutritional status’, ‘BMI’, ‘obesity’, ‘diet’, ‘nutrition’, dietary pattern’, ‘food’, ‘nutrient’, ‘fatty acids’, ‘antioxidant’, ‘supplementation’, ‘vitamin C’, ‘vitamin E’,’ vitamin A’, ‘folate’, ‘zinc’, ‘selenium’, ‘L-carnitine’, ‘glutathione’, ‘coenzyme Q10‘, ‘N-acetylcysteine’, ‘lycopene’. Reference lists of studies extracted from the primary electronic search were used to identify additional relevant studies.
|Semen factor||Site restriction (95% rely on times)|
|Semen volume||1.5 ml (step one.4–step one.7)|
|Overall sperm count||39 mil each ejaculate (33–46)|
|Spunk attention||15 billion per ml (12–16)|
|Powers||58% live (55–63)|
|Progressive motility||32% (31–34)|
|Complete (modern + nonprogressive) motility||40% (38–42)|
|Morphologically typical models||cuatro.0% (step 3.0–4.0)|